|Institution||Philipps-University Marburg, Germany|
Malte Buchholz obtained his PhD in molecular biology in 1998. He is group leader and Head of Basic Research at the Department of Gastroenterology, Endocrinology and Metabolism, University Hospital Marburg, Philipps-University of Marburg, Germany (http://www.uni-marburg.de/fb20/gastroendokrinol/forschung?language_sync=1). His research interests focus on transcriptome analyses and molecular diagnostics of gastrointestinal tumors, functional genomic analyses of pancreatic cancer, and molecular determinants of tumor-host interactions. Among others, he has performed global gene expression analyses of stromal cell populations from different organs as well as microdissected tumor cells and pre-neoplastic lesions from pancreatic ductal adenocarcinoma (PDAC) patients. These data formed an important basis for the design of specialized cDNA arrays which are suitable to distinguish between different forms of pancreatico-biliary tumors with high diagnostic precision. In addition, his group has identified and characterized novel candidate genes with central roles in the physiology of pancreatic tumor cells.
Dr. Buchholz has been intimately involved in the management and coordination of several national and international multidisciplinary research projects, including the BMBF-funded NGFNplus project “PaCa-Net” as well as the EU FP7 collaborative projects “MolDiag-PaCa” and “European Pancreatic Cancer-Tumor-Microenvironment Network (EPC-TM-Net)”. He is currently co-coordinator of the EU FP7 large-scale integrative project “CAM-PaC” (Integrative Analysis of Gene Functions in Cellular and Animal Models of Pancreatic Cancer)( http://www.cam-pac.eu/) and “Bio-PaC” (Biomarkers of tumor recurrence in pancreatic cancer).
Within COST Action BM1204 EU_Pancreas – An integrated European platform for pancreas cancer research, Dr. Buchholz is co-leader of WG1 (Harmonization of research tools) as well as member of WG3 (Translational Research).